Antetokounmpo scored 36 points on 15-for-26 shooting with 12 rebounds and five assists. Davion Mitchell added 18 and Bobby Portis had 11 off the bench. Miami shot 38% and made 15 of 51 3-pointers. Andrew Wiggins scored eight on 3-for-12 shooting. The Heat did grab 18 offensive rebounds, and they turned the ball over only 12 times to Detroit's 20, but the Pistons ran for 22 fast-break points and had 34 assists.
Detroit's bench carried a big share of the scoring. Reed went 8 for 11, Daniss Jenkins added 15 points and five assists, and Isaiah Joe scored 12. The Pistons led for 98% of the game and by as many as 23.
The Heat have allowed 259 points in two games, a franchise worst to open a season, and are 0-2 for the eighth time in their history, per the AP. It is also the first time Antetokounmpo has played in his team's first two games and lost both.
Detroit had injury worries. Ausar Thompson left in the third quarter after an awkward fall, and Jalen Duren played 10 first-half minutes before leaving with a right thigh issue. The Pistons visit Philadelphia on Sunday. Miami plays at Charlotte on Saturday.