Three Angels home runs put Boston six runs behind before the Red Sox could answer Wednesday. Roman Anthony and Wilyer Abreu homered to bring them back into the game, but Los Angeles held on for a 6–4 win at Fenway Park.

The decisive damage came in the third inning. Zach Neto hit a three-run homer to left, scoring Oswald Peraza and Denzer Guzman. Jose Siri followed later in the inning with a two-run shot to right-center that brought home Mike Trout. Boston went from a scoreless game to a five-run deficit in that inning.

Guzman added a solo homer in the fourth, giving Los Angeles a 6–0 lead. The Angels would not score again, but their three home runs accounted for all six runs. Neto finished 2 for 3 with three RBIs, Siri went 2 for 4 with two RBIs, and Guzman had three hits in four at-bats and scored twice.

Anthony supplied Boston’s first response in the fifth. His two-run homer to right brought home Jarren Duran and cut the deficit to four. Abreu’s solo shot to center in the sixth made it 6–3, leaving the Red Sox within one swing of tying the game if they could put two runners aboard.

Boston instead added its last run in the ninth. Duran drew a walk and scored on Nate Eaton’s single to right. Anthony then flied out to right to end the game, leaving the tying run at the plate. The Red Sox had scored four unanswered runs, but the early deficit held up.

Jake Bennett allowed six earned runs on nine hits over 5⅓ innings. He struck out two, walked one and surrendered all three Angels homers. Boston’s bullpen kept the game close: Wyatt Olds worked 1⅔ scoreless innings, and Jovani Moran and Alec Gamboa each added a scoreless inning.

Ryan Johnson gave Los Angeles six innings, allowing three runs on five hits with five strikeouts and one walk. Boston’s two homers came against him. Four relievers handled the final three innings, with Ben Joyce allowing the ninth-inning run before finishing the game.

Duran was Boston’s only hitter with more than one hit. He went 2 for 3, walked once and scored twice. Anthony finished 1 for 5 with two RBIs, and Abreu was 1 for 3 with a walk and his solo homer. Los Angeles outhit Boston 12–8.

The late innings offered Boston a route back: its relievers stopped the scoring, and the lineup chipped away in three separate innings. The difference remained the Angels’ concentrated power in the third and fourth. Boston’s two home runs produced three runs; Los Angeles’ three produced six.